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Spontaneous regression of primary cutaneous Epstein–Barr virus‐positive, CD30‐positive anaplastic large T‐cell lymphoma in a heart‐transplant recipient
Author(s) -
Chiu L. S.,
Choi P. C. L.,
Luk N. M.,
Chang M.,
Tang W. Y. M.
Publication year - 2009
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2008.03145.x
Subject(s) - cd30 , anaplastic large cell lymphoma , medicine , lymphoma , epstein–barr virus , virus , gammaherpesvirinae , pathology , immunology , herpesviridae , viral disease
Summary We presented a rare case of primary cutaneous Epstein–Barr virus‐positive, CD30‐positive anasplastic large cell lymphoma in a 64‐year‐old man who had received a heart transplant 11 years previously. The first presenting symptom was the appearance of erythematous skin nodules on the right leg. The lesions subsided with dose reduction of immunosuppressant alone. There was no recurrence 9 months after the first diagnosis. We propose that dose reduction of immunosuppressant alone may be an effective treatment for localized, indolent, post‐transplant‐related primary cutaneous lymphoma. Our case shows the importance of regular surveillance of skin cancer in patients who have received organ transplant.