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Calciphylaxis in a patient with normal renal function: response to treatment with sodium thiosulfate
Author(s) -
Hackett B. C.,
McAleer M. A.,
Sheehan G.,
Powell F. C.,
O’Donnell B. F.
Publication year - 2009
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2008.02877.x
Subject(s) - calciphylaxis , sodium thiosulfate , medicine , renal function , hypoparathyroidism , thiosulfate , kidney disease , surgery , disease , urology , chemistry , inorganic chemistry , sulfur , organic chemistry
Summary Calciphylaxis is a rare, life‐threatening cause of skin necrosis. The condition is primarily reported in patients with end‐stage renal disease, and is associated with significant morbidity and mortality. Treatment has mainly been empirical. We report a case of calciphylaxis in a patient with normal renal function and hypoparathyroidism, who responded to treatment with sodium thiosulfate. To our knowledge, this is the first reported case of the use of sodium thiosulfate to treat calciphylaxis in a patient with normal renal function.