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Interstitial granulomatous dermatitis: a misdiagnosed cutaneous form of systemic lupus erythematosus?
Author(s) -
Blaise S.,
Salameire D.,
Carpentier P. H.
Publication year - 2008
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2008.02774.x
Subject(s) - medicine , immunoglobulin d , dermatology , etiology , lupus erythematosus , granuloma annulare , pathology , immunology , antibody , b cell
Summary Interstitial granulomatous dermatitis (IGD) is a recently described, rare dermatological entity. The clinical features are diverse and the precise aetiology is unknown. We present a rare and atypical case of IGD in a patient with systemic lupus erythematosus (SLE). A 26‐year‐old woman had been diagnosed with SLE when she was 15 years old. The diagnosis was based on cutaneous, articular, pulmonary, haematological and immunological features. The patient presented with a cutaneous diffuse macular eruption on the limbs, appearing in a cockade (rosette) pattern with a violaceous centre and erythematous surround. The face and trunk were spared. The cutaneous histological features led us to consider a diagnosis of IGD. The lesions disappeared after 15 days of systemic steroid therapy. This case is a new clinical form of IGD with an atypical location and clinical presentation. IGD has usually been associated with drug‐related adverse reactions and autoimmune diseases. Reports in the literature of IGD in patients with SLE are rare.