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Disseminated blue naevus and malignant blue naevus associated with excessive aromatase syndrome
Author(s) -
Lobo A. Z. C.,
Martin R.M.,
Belda W.,
Michi M. M.,
Ar M.,
FestaNeo C.,
Sotto M. N.,
Vilela M. A. C.,
Sanches J. A.
Publication year - 2008
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2008.02720.x
Subject(s) - medicine , dermatology , blue nevus , aromatase , nevus , cancer research , melanoma , breast cancer , cancer
Summary We report a case of a 17‐year‐old boy who had a giant congenital blue naevus with multiple satellite pigmented lesions. Later the patient developed melanoma arising in the pre‐existing lesion. He also had gynaecomastia and was diagnosed as having aromatase excess syndrome. To our knowledge, the association of these two rare conditions has not been previously reported. Further studies should be performed to investigate this unusual combination, which may have a genetic, endocrine or local cutaneous link leading to its occurrence.