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Disseminated clustered juvenile xanthogranuloma: an unusual morphological variant of a common condition
Author(s) -
Kaur M. R.,
Brundler M. A.,
Stevenson O.,
Moss C.
Publication year - 2008
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2008.02705.x
Subject(s) - juvenile xanthogranuloma , juvenile , pathology , medicine , biology , dermatology , genetics , histiocyte
Summary Juvenile xanthogranuloma (JXG) is a benign, self‐healing non‐Langerhans cell histiocytosis of unknown aetiology, most commonly occurring in infants and children. JXG is characterized by solitary or multiple yellowish cutaneous nodules, the two common clinical variants being a small nodular form and large nodular form, which frequently coexist. Unusual morphological presentations include keratotic, lichenoid, pedunculated, subcutaneous, clustered, plaque‐like and giant lesions. We describe the first reported case of ‘disseminated’ clustered juvenile xanthogranuloma presenting in an infant.