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Subcutaneous sarcoidosis localised to sites of previous desensitizing injections
Author(s) -
Marcoval J.,
Moreno A.,
Mañá J.
Publication year - 2008
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2007.02571.x
Subject(s) - medicine , sarcoidosis , asymptomatic , dermatology , injection site , desensitization (medicine) , lesion , adverse effect , systemic disease , pathology , immunopathology , receptor
Summary Subcutaneous sarcoidosis is a specific cutaneous lesion of systemic sarcoidosis that is rarely reported. Clinically, it is characterized by multiple, asymptomatic subcutaneous nodules mainly located on the forearms. Adverse effects of desensitization injections mostly consist of local transient reactions. Nodular lesions may also develop at the site of injection; these have been attributed to the aluminium hydroxide contained by many vaccines. We report a 49–year old woman with a history of two outbreaks of acute sarcoidosis (Löfgren syndrome) in 1994 and 1999, who developed lesions of subcutaneous sarcoidosis in the upper part of both arms, at the sites of desensitization injections for extrinsic asthma immunotherapy.