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Mycobacterium marinum infection complicating Crohn's disease, treated with infliximab
Author(s) -
Fallon J. C.,
Patchett S.,
Gulmann C.,
Murphy G. M.
Publication year - 2008
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2007.02564.x
Subject(s) - mycobacterium marinum , infliximab , medicine , crohn's disease , disease , necrosis , mycobacterium , immunology , surgery , pathology , tuberculosis
Summary Tumour necrosis factor‐α inhibitors including infliximab are often used to treat a number of recalcitrant medical conditions. These agents are increasingly associated with infections, particularly mycobacterial infections. We report sporotrichoid spread of Mycobacterium marinum in a 37‐year‐old woman with Crohn's disease, who had been receiving infliximab infusions for 2 years. An infection had spread up the right leg, after she had been swimming on holiday in the Canary Islands. M. marinum was cultured from the lesions and also identified by PCR on formalin‐fixed tissue. To our knowledge, this is the first report of M. marinum occurring in a patient receiving infliximab.