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A case of cutaneous extravascular necrotizing granuloma without systemic manifestations
Author(s) -
Newell E. L.,
Mallipeddi R.,
Murdoch M. E.,
Groves R.,
Black M. M.,
Robson A.
Publication year - 2007
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2007.02426.x
Subject(s) - medicine , granuloma , dermatology , pathology
Summary Cutaneous extravascular necrotizing granuloma, an unusual palisading dermal granuloma, was first described by Churg and Strauss in 1951 in association with the syndrome of allergic granulomatosis (Churg–Strauss syndrome), for which it was though to be pathognomonic. It has subsequently been described in association with a number of autoimmune and immunoreactive diseases, and is regarded as a cutaneous marker of systemic pathology. To our knowledge, only one patient has been reported with clinical features confined to the skin. We report a 46‐year‐old woman with recurrent cutaneous lesions over a 10‐year period and the classic histopathological pattern, but no underlying systemic disease.