Premium
Pyoderma gangrenosum as initial manifestation of Graves’ disease
Author(s) -
Livideanu C.,
Lipsker D.,
Paul C.,
Juillard J.,
Schubert B.
Publication year - 2006
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2006.02184.x
Subject(s) - pyoderma gangrenosum , medicine , clearance , ciclosporin , colchicine , inflammatory bowel disease , dermatology , graves' disease , disease , autoimmune disease , surgery , chemotherapy , urology
Summary Pyoderma gangrenosum (PG) is an uncommon ulcerative condition. It is most commonly associated with inflammatory bowel disease, haematological malignancies and autoimmune disease. We report on two patients have developed PG during the initial course of Graves' disease (GD), prior to treatment of this condition. The lesions completely cleared with treatment by colchicine in the first case and with oral ciclosporin in the second case. The report emphasizes that a diagnostics of PG should be considered in patients with GD and skin ulcers.