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Microscopic polyarteritis presenting with skin necrosis in a patient with sickle‐cell disease
Author(s) -
Dawe S. A.,
Powell S. E.,
Short K. A.,
Salisbury J.,
Roberts J.,
Creamer D.
Publication year - 2006
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2005.01950.x
Subject(s) - medicine , necrosis , histopathology , differential diagnosis , disease , polyarteritis nodosa , dermatology , vasculitis , ankle , pathology , systemic disease
Summary A 20‐year‐old Caribbean woman with sickle cell anaemia was admitted with a 4‐day history of fever and a painful swollen right ankle. She rapidly developed skin necrosis. The differential diagnosis is discussed. This case illustrates the difficulty in identifying the cause of cutaneous necrosis in an acutely ill patient. In our patient, histopathology implicated a vasculitic process, which was subsequently identified as a manifestation of microscopic polyarteritis.