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Subacute cutaneous lupus erythematosus: a paraneoplastic dermatosis?
Author(s) -
Chaudhry S. I.,
Murphy L.A.,
White I. R.
Publication year - 2005
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2005.01900.x
Subject(s) - medicine , subacute cutaneous lupus erythematosus , dermatology , malignancy , lupus erythematosus , head and neck , pathology , connective tissue disease , autoimmune disease , immunology , antibody , disease , surgery
Summary Subacute cutaneous lupus erythematosus (SCLE) is characterized by clinical, laboratory and immunological features different from those of systemic lupus erythematosus (SLE). We describe the case of a patient with a 2‐year history of SCLE that demonstrated a close temporal relationship with a squamous cell malignancy of the head and neck. This association has not been previously reported. We also review the evidence for SCLE as a ‘paraneoplastic dermatosis’ and discuss the criteria for diagnosis and possible pathogenesis.