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Disseminated Kaposi's sarcoma associated with idiopathic CD4+ lymphocytopenia and low dose steroid therapy
Author(s) -
Fierro M. T.,
Savoia P.,
Quaglino P.,
Novero D.,
Bernengo M. G.
Publication year - 2005
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2005.01795.x
Subject(s) - lymphocytopenia , sarcoma , medicine , kaposi's sarcoma , dermatology , pathology , human herpesvirus , lymphocyte
Summary A case of disseminated Kaposi sarcoma in a 76‐year‐old woman treated with low‐dose steroids for a seronegative polyarthritis is described. HIV serology was negative, whereas PCR for HHV‐8 was positive. The patient presented with a profound reduction in the peripheral blood CD4+ cell count and a decrease in serum immunoglobulins and was diagnosed as having idiopathic CD4+ lymphocytopenia. The clinical picture was characterized by limited cutaneous lesions with typical features of KS associated with widespread visceral involvement and unusually aggressive behaviour.