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Localized granulomatous reaction to a semi‐permanent hyaluronic acid and acrylic hydrogel cosmetic filler
Author(s) -
Sidwell R. U.,
Dhillon A. P.,
Butler P. E. M.,
Rustin M. H. A.
Publication year - 2004
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2004.01625.x
Subject(s) - hyaluronic acid , filler (materials) , cosmetic techniques , acrylic acid , soft tissue , skin reaction , medicine , dermatology , surgery , materials science , composite material , polymer , anatomy , monomer
Summary Dermalive, an injectable skin filler composed of a combination of synthetic hyaluronic acid and acrylic hydrogel particles was recently developed for soft tissue augmentation. Dermalive produces longer term results than temporary injectable fillers and is associated with a reportedly low incidence of adverse reactions. We describe a marked local reaction to the injection of Dermalive in the nasolabial fold developing within 4 months with histological confirmation of a granulomatous response. To our knowledge there has been only one previous report of a local granulomatous reaction to Dermalive.