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Cutaneous infection by Scedosporium apiospermum and its successful treatment with itraconazole
Author(s) -
LIU Y.F.,
ZHAO X.D.,
MA C.L.,
LI C.X.,
ZHANG T.S.,
LIAO W.J.
Publication year - 1997
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1997.tb01062.x
Subject(s) - scedosporium apiospermum , itraconazole , medicine , dermatology , mycosis , lesion , surgery , terbinafine , antifungal , voriconazole
Summary We report the case of a 42‐year‐old man with a 13‐year history of bilateral faciocervical infiltrative erythema, which had been misdiagnosed as tuberculoderma and which had failed to respond to treatment with adrenal corticosteroids and antituberculotics. On admission to the department, Scedosporium apiospermum was identified on lesion biopsies and fungus cultures as the causative agent and a diagnosis of cutaneous infection by S. apiospermum was made. This is the first report of chronic skin granuloma caused by S. apiospermum in China. Treatment with oral itraconazole (100–400mg/day) led to clinical cure within 4 months.