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Transient leukaemia cutis in chronic lymphocytic leukaemia *
Author(s) -
WAKELIN S.H.,
YOUNG E.,
KELLY S.,
TURNER M.
Publication year - 1997
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1997.tb01045.x
Subject(s) - medicine , dermatology , general hospital , family medicine
Summary Leukaemia cutis arises from cutaneous infiltration by neoplastic leukocytes or their precursors. Recent evidence suggests that this sign does not necessarily herald a poor prognosis. We describe a 72‐year‐old woman with B‐cell chronic lymphatic leukaemia who developed a papular eruption of her breast at the site of a recent herpetic eruption. Histology and immunostaining showed a dense dermal B‐cell infiltrate in keeping with leukaemia cutis. The papules cleared in 6 months without treatment, leaving atrophic scars. The histological features and possible aetiological mechanisms of post‐herpetic papular eruptions in chronic lymphatic leukaemia are reviewed.