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Multiple endocrine neoplasia type 1 presenting as rosacea
Author(s) -
CREAMER J.D.,
WHITTAKER S.J.,
GRIFFITHS W.A.D.
Publication year - 1996
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1996.tb00047.x
Subject(s) - rosacea , multiple endocrine neoplasia , medicine , dermatology , endocrine system , biology , hormone , acne , genetics , gene
Summary We present a ease of malignant carcinoid initially diagnosed as rosacea. This patient was later found to have an additional functioning parathyroid tumour. Although a pituitary tumour was nor identified, the association represents a probable case of multiple endocrine neoplasia type 1 (MEN 1). This autosomal dominant syndrome is characterized by tumours of the pancreas, parathyroid and pituitary. Inoperable carcinoid rumour is best treated with a long‐acting somatostatin analogue, octreotide. A diagnosis of MKN I has important connotations for the proband's first‐degree relatives, who should be entered into an appropriate screening programme.