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Phenytoin–induced toxic epidermal necrolysis: a case report
Author(s) -
CREAMER J.D.,
WHITTAKER S.J.,
KERRMUIR M.,
SMITH N.P.
Publication year - 1996
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1996.tb00032.x
Subject(s) - toxic epidermal necrolysis , phenytoin , medicine , dermatology , antibiotics , erythroderma , anticonvulsant , anesthesia , surgery , epilepsy , microbiology and biotechnology , biology , psychiatry
Summary We present a case of phenytoin‐induced toxic epidermal necrolysis resulting in 60–70% skin involvement. Systemic corticosteroids and prophylactic antibiotics used initially were discontinued, and subsequent management concentrated on intensive supportive treatment. The patient survived, but is left with disabling ocular complications.