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Serum sickness‐like illness following streptokinase therapy. A case report
Author(s) -
CREAMER J.D.,
MCGRATH J.A.,
WEBBPEPLOE M.,
SMITH N.P.
Publication year - 1995
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1995.tb01379.x
Subject(s) - medicine , streptokinase , serum sickness , complication , myocardial infarction , immunology , dermatology , surgery , intensive care medicine , antibody
Summary We report a patient who developed a serum sickness‐like illness characterized by fever, arthritis, haematuria and a purpuric eruption 7 days following streptokinase therapy for myocardial infarction. Blood tests demonstrated increased circulating immune complexes. The skin involvement resulted in extensive, painful cutaneous infarction with secondary bacterial infection. Serum sickness is an uncommon but recognized complication of streptokinase therapy.