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Mitozantrone‐induced onycholysis. A series of five cases
Author(s) -
CREAMER J.D.,
MORTIMER P.S.,
POWLES T.J.
Publication year - 1995
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1995.tb01377.x
Subject(s) - onycholysis , dermatology , series (stratigraphy) , medicine , paronychia , biology , paleontology
Summary The anthracenedione cytotoxic agent, mitozantrone, has a well‐established place in the treatment of acute leukaemia, lymphoma, breast carcinoma and other malignant tumours. In general it is well tolerated apart from myelosuppression and dose‐related cardiotoxicity. Alopecia is a common side‐effect with mitozantrone but otherwise the skin and its appendages are rarely affected. We present five cases of mitozantrone‐induced onycholysis.