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Reticular pigmented genodermatosis with milia—a special form of Naegeli–Franceschetti–Jadassohn syndrome or a new entity?
Author(s) -
TZERMIAS C.,
ZIOGA A.,
HATZIS I.
Publication year - 1995
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1995.tb01336.x
Subject(s) - genodermatosis , milia , medicine , dermatology , hyperpigmentation , photodarkening , biochemistry , chemistry , fiber laser , organic chemistry , gene , fiber
Summary A 19‐year‐old woman with a condition since birth, comprising reticular hyperpigmentation, palmoplantar hyperkeratosis, dental anomalies, hypoplasia of dermatoglyphics and a slight yellowish hue to the nails is presented. Her father and grandfather were similarly affected. The reticular hyperpigmentation, although generalized, was more intense on the flexural areas where extensive milia formation was also observed. This case represents an unusual genodermatosis. The milia formation and the presence of normal perspiration indicate a special form of Naegeli–Franceschetti–Jadassohn (NFJ) syndrome, or a new entity close to the NFJ syndrome. The differential diagnosis from other congenital reticulate pigmentary disorders is discussed.