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Coexisting lichen planus and subacute cutaneous lupus erythematosus
Author(s) -
GRABBE S.,
KOLDE G.
Publication year - 1995
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1995.tb01315.x
Subject(s) - subacute cutaneous lupus erythematosus , medicine , histopathology , dermatology , lupus erythematosus , skin lesion , pathology , systemic lupus erythematosus , direct fluorescent antibody , pathophysiology , autoimmune disease , connective tissue disease , disease , immunology , antibody
Summary We report a patient who presented with annular erythematous skin lesions and generalized lichenoid papules. The clinical picture as well as histopathology, immunofluorescence and laboratory findings indicated coexistence of subacute cutaneous lupus erythematosus (SCLE) and extensive generalized lichen planus (LP). Clinically and historically, SCLE‐like lesions appeared to progress into LP‐like lesions, supporting the concept of a common autoimmune pathophysiology in these disorders. Treatment with cyclosporin A (2.5 mg/kg body weight) resulted in a significant remission of the inflammatory skin lesions.