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Erythrodermic mycosis fungoides treated with total body irradiation and autologous bone marrow transplantation
Author(s) -
STERLING J.C.,
MARCUS R.,
BURROWS N.P.,
ROBERTS S.O.B.
Publication year - 1995
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1995.tb01291.x
Subject(s) - mycosis fungoides , medicine , total body irradiation , bone marrow transplantation , bone marrow , whole body irradiation , transplantation , dermatology , pathology , lymphoma , surgery , chemotherapy , cyclophosphamide
Summary We describe a middle‐aged man with aggressive erythrodermic mycosis fungoides whose responses to several well‐established therapies for the disease were either poor or short‐lived. Infusion of antibodies engineered against cells expressing the CD4 molecule produced little response. Total body irradiation coupled with autologous bone marrow transplantation led to an encouraging but unfortunately unsustained improvement.