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Leucopenia, thrombocytopenia and lymphadenopathy associated with sulphasalazine
Author(s) -
MCKENNA K.K.,
BURROWS D.
Publication year - 1994
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1994.tb02699.x
Subject(s) - medicine , dermatology , immunology
Summary We report a 19‐year‐old woman with psoriasis who developed a severe allergic reaction within 1 week of commencement of sulphasalazine; her skin becoming erythrodermic with associated lymphadenopathy, leucopenia and thrombocytopenia. Clinical signs and haematological abnormalities rapidly returned to normal on discontinuation of sulphasalazine. It is important to monitor carefully hacmatological indices in the early stages of treatment with this drug.