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Neonatal lupus erythematosus
Author(s) -
JENKINS R.E.,
KURWA A.R.,
ATHERTON D.J.,
BLACK M.M.
Publication year - 1994
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1994.tb02695.x
Subject(s) - medicine , vitiligo , dermatology , connective tissue disease , lupus erythematosus , systemic lupus erythematosus , connective tissue , mixed connective tissue disease , pathology , immunology , autoimmune disease , disease , antibody
Summary We present a case of neonatal lupus erythematosus (NLE) in a black infant presenting with symmetrical depigmented macules on the face resembling vitiligo. NLE is a rare condition affecting newborn infants of mothers who have connective tissue disease, with or without autoantibodies to extractable nuclear antigens Ro (SS‐A), La (SS‐B) or ribonucleoproteins. Infants present with cutaneous lesions or congenital heart block or both. The skin lesions are usually annular and erythematous and transient and resemble those of subacute cutaneous lupus erythematosus. The presentation of this patient was therefore striking.