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Uncomplicated pregnancy and birth of a healthy child by a woman with systemic lupus erythematosus and anti‐U1RNP, anti‐PCNA/cyclin, anti‐dsDNA and anti‐phospholipid autoantibodies
Author(s) -
AUERGRUMBACH P.,
RAMSCHAK H.,
KAINER F.
Publication year - 1994
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1994.tb02692.x
Subject(s) - autoantibody , medicine , pregnancy , immunology , antibody , biology , genetics
Summary We report the course of a pregnancy of a 21‐year‐old primipara and primigravida with systemic lupus erythematosus (SLE) and anti‐U1RNP, anti‐PCNA/cyclin, anti‐dsDNA and anti‐phospholipid autoantibodies. The pregnancy was normal and a healthy child was born at term. The risks associated with the HLA phenotype of of the mother and with these autoantibodies were previously unknown. We present a model for risk assessment in patients with rare laboratory features of SLE.