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Primary anetoderma: phagocytosis of elastic fibres by macrophages
Author(s) -
ZAKI I.,
SCERRI L.,
NELSON H.
Publication year - 1994
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1994.tb02688.x
Subject(s) - phagocytosis , medicine , pathogenesis , pathology , asymptomatic , etiology , electron microscope , immunology , physics , optics
Summary We report a 22‐year‐old female with a 2‐year history of increasingly numerous well‐circumscribed, asymptomatic skin lesions. The clinical and histological features were consistent with anetoderma and investigations failed to reveal any associated underlying disorders. Electron microscopy of abnormal skin showed phagocytosis of elastic fibres by macrophages. Although the aetiology of primary anetoderma remains unknown, this finding suggests that phagocytic destruction of elastic fibres plays a major role in its pathogenesis.