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Cutaneous granuloma with ataxia telangiectasia—a case report and review of literature
Author(s) -
JOSHI R.K.,
AL ASIRI R.H.,
HALEKM A.,
ABANMI A.,
PATEL C.K.
Publication year - 1993
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1993.tb02251.x
Subject(s) - histopathology , dermis , pathology , ataxia telangiectasia , medicine , granuloma , telangiectasia , atrophy , dermatology , biology , dna , genetics , dna damage
Summary A patient is reported who had ataxia telangiectasia with multiple cutaneous lesions mainly on the limbs, which showed atrophy and scarring. Histopathology of these skin lesions showed tuberculoid granulomas without frank collagen necrobiosis in the dermis. Chromosomal analysis revealed a translocation between 7 and 14 as well as deletion of chromosomes 4 and 6.