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Immunohistopathological spectrum in cutaneous tuberculosis
Author(s) -
SEHGAL V. N.,
GUPTA R.,
BOSE M.,
SAHA K.
Publication year - 1993
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1993.tb02204.x
Subject(s) - tuberculosis , medicine , dermatology , spectrum (functional analysis) , pathology , physics , quantum mechanics
Summary Granulomas of lupus vulgaris were characterized by a raised CD4 + /CD8 + ratio, while in scrofuloderma this was significantly decreased. Tuberculosis verrucosa cutis showed intermediate changes. These immunological variations suggest that cutaneous tuberculosis forms a spectrum with strong cell‐mediated immunity seen in lupus vulgaris, and weaker cell‐mediated responses in scrofuloderma; tuberculosis verrucosa cutis is intermediate between the two.