Premium
Pemphigoid gestationis—response to chemical oophorectomy with goserelin
Author(s) -
GARVEY M.P.,
HANDFIELDJONES S.E.,
BLACK M.M.
Publication year - 1992
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1992.tb00256.x
Subject(s) - medicine , oophorectomy , goserelin , prednisolone , luteinizing hormone , pregnancy , hormone , gynecology , surgery , endocrinology , hysterectomy , cancer , biology , breast cancer , genetics
Summary A 46‐year‐old Caucasian female presented in January 1991 with a 17‐year history of severe pemphigoid gestationis. She had been on systemic steroids for 10 years since her last pregnancy in 1981 and required doses of 20–80 mg prednisolone daily to control her disease. A chemical oophorectomy was induced using a new lutenizing hormone releasing hormone (LHRH) analogue known as goserelin. A complete remission occurred within 6 months of initiating this treatment and the systemic steroids were discontinued.