Premium
Epidermolysis bullosa acquisita presenting with localized facial blisters
Author(s) -
WOO LEE CHANG,
MIN JUN KYUNG
Publication year - 1992
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1992.tb00234.x
Subject(s) - epidermolysis bullosa acquisita , blisters , bulla (seal) , medicine , prednisolone , dermatology , biopsy , skin biopsy , pathology , antibody , surgery , autoantibody , immunology , lung
Summary A 44‐year‐old woman presented with blisters on her face of 1‐month's duration. A biopsy showed a subepidermal bulla with a dermal infiltrate of inflammatory cells and thick linear deposits of immunoreactants along the dermo‐epidermal junction. Using Western immunoblots, the patient's IgG antibody was found to recognize type VII procollagen. Moderate doses of oral prednisolone resulted in a complete remission, without a recurrence for more than 3 years.