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Malignant hidradenoma—a case report demonstrating insidious histological and clinical progression
Author(s) -
BIDDLESTONE L.R.,
MCLAREN K.M.,
TIDMAN M.J.
Publication year - 1991
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1991.tb01241.x
Subject(s) - hidradenoma , atypia , medicine , pathology , sweat gland , eccrine sweat gland , eccrine sweat , surgical excision , sweat , surgery
Summary A histologically benign hidradenoma, occurring in a 15‐year‐old female inadequately excised at first procedure, recurred locally over the course of 11 years and exhibited first local and subsequently regional metastatic spread. The insidious progression was associated with increasing cytological atypia and alteration of epithelial antigenic expression. In view of the rarity of malignant sweat‐gland tumours and consequent lack of a specific treatment protocol, this case serves to emphasize the importance of adequate primary local excision, with histological confirmation of clearance, in the management of sweat‐gland tumours.