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Skin ulceration as sole manifestation of Langerhans‐cell histiocytosis
Author(s) -
MODI D.,
SCHULZ E.J.
Publication year - 1991
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1991.tb00351.x
Subject(s) - langerhans cell histiocytosis , groin , axilla , medicine , dermatology , histiocytosis , pathology , histiocyte , stain , disease , surgery , staining , cancer , breast cancer
Summary A 65‐year‐old black woman presented with skin ulceration of 5 years' duration which affected the left axilla, left groin, intergluteal folds and ano‐perineal region. The diagnosis of Langerhans‐cell histiocytosis (LCH) was confirmed by light and electron‐microscopic findings and a positive S‐100 stain. Extensive investigations failed to reveal any evidence of systemic involvement. A review of the literature suggests that this clinical picture as the sole manifestation of the disease is rare.