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Alteration of cartilagenous proteoglycan in psoriasis
Author(s) -
YUTANI Y.,
KONO T.,
ISHII M.,
CHANOKI M.,
CHANOKI Y.,
ASADA K.,
SHIMAZU A.,
HAMADA T.
Publication year - 1991
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1991.tb00287.x
Subject(s) - psoriasis , proteoglycan , medicine , dermatology , biology , immunology , cartilage , anatomy
Summary Articular tissue was obtained at surgery for a femoral neck fracture in a patient with psoriasis without arthritis. The proteoglycan of the cartilage of the sample was analysed biochemically. Normal cartilage is known to produce two types of proteoglycan monomers (fast‐ and slow‐sedimenting groups), which are distinguishable by density‐gradient ultracentrifugation. In the psoriatic cartilage analysed in the present study, it was shown that the former group was absent and only the latter group remained.