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Hairy leucoplakia—a clinical, histopathological and ultrastructural study in 33 patients
Author(s) -
ARAGÜES M.,
SANCHEZ PEREZ J.,
FRAGA J.,
BURGOS E.,
NOGUERADO A.,
GARCIA DIEZ A.
Publication year - 1990
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1990.tb02107.x
Subject(s) - garcia , section (typography) , medicine , humanities , history , library science , art , advertising , computer science , business
Summary Thirty‐three cases of hairy leucoplakia (ML) in HIV‐positive patients were studied. The most frequent clinical presentation was the development of corrupted plaques on the lateral sides of the tongue without spiculations on the surface. In all biopsies, herpetic‐type viral inclusions were found. In 12 out of 14 cases in whom an electro‐microscopic study was carried out, only viral particles of the herpes group were found. Human papillomavirus (HPV) was not demonstrated, although by means of immunohistochemistry, positive labelling for HPV was found in 95% of the cases. The aetiopathological significance of these findings remains to be evaluated.