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Porphyria cutanea tarda and scleroderma—chance association or related disease: a case report
Author(s) -
SIGAL M.,
NAHUM H.D.,
CRICKX B.,
BILET S.,
MOURIERMASSICOT CH.,
BELAICH S.
Publication year - 1990
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1990.tb02091.x
Subject(s) - porphyria cutanea tarda , medicine , scleroderma (fungus) , dermatology , disease , pathology , inoculation
Summary The concurrence of systemic scleroderma and porphyria cutanea tarda (PCT) seems very rare. Only six cases have been reported to our knowledge. On the other hand, cutaneous sclerodermatous lesions in PCT occur more frequently and can affect 1·8‐18% of cases. 1,2 These observations raise the problem of a possible physiopathological relation between scleroderma and PCT. In fact, Grossman and colleagues 3 have found anti‐nuclear antibodies (ANA) in 38% of patients so tested. In the present report, the association of systemic scleroderma and PCT with Sjögren's syndrome and anti‐RNP antibodies raises further questions concerning the relationship between PCT and auto‐immune diseases.