Thromboangiitis obliterans (Bürger's disease) in a woman—a case report and review of the literature

Summary We report the case of a 43‐year‐old woman, a longstanding heavy cigarette smoker, who developed Bürger's disease, leading to mid‐thigh amputation of her left leg;. After she gave up smoking her disease was arrested hut Raynaud's phenomenon continues to affect her hands and right foot. In reviewing the literature, we found only 25 previous well‐documented cases of Burger's disease occurring in females that would satisfy clinical, angiographic and histological criteria to make this diagnosis probable.