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Langerhans cells in delayed skin reactions to inhalant allergens in atopic dermatitis—an electron microscopic study
Author(s) -
NAJEM N.,
HULL D.
Publication year - 1989
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1989.tb00936.x
Subject(s) - atopic dermatitis , langerhans cell , immunology , intoxicative inhalant , peripheral blood mononuclear cell , medicine , contact dermatitis , dermatology , allergy , antigen , chemistry , biology , toxicology , in vitro , biochemistry
Summary Langerhans cells at the site of patch rests to inhaled allergens in patients with atopic dermatitis were investigated. Within 24 h the Langerhans cells showed increased cellular activity and became apposed to mononuclear cells. This supports the view that Langerhans cells are involved in antigen presentation in atopic dermatitis.