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Acne fulminans with circulating immune complexes and leukaemoid reaction treated with steroids and azathioprine
Author(s) -
WOOLFSON H.
Publication year - 1987
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1987.tb01952.x
Subject(s) - medicine , azathioprine , acne , dermatology , erythema , immune system , erythema nodosum , surgery , immunology , disease
Summary A 16‐year‐old boy developed within a few days severe acne fulminans. Unlike previously described cases, moderate steroid therapy did not give control. He required both high dosage steroid and azathioprine. This combined therapy took 10 months before full remission of his systemic illness and cutaneous inflammatory activity was achieved. He has been left with extensive hypertrophic and atrophic scarring. During the course of the illness he had a sustained leukaemoid reaction and circulating immune complexes. The latter has not previously been described in acne fulminans in the absence of accompanying erythema nodosum.