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Acanthosis nigricans and diabetes mellitus in a patient with Klinefelter's syndrome: a reaction to methyltestosterone
Author(s) -
SHUTTLEWORTH D.,
WEAVIND G.P.,
GRAHAMBROWN R.A.C.
Publication year - 1987
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1987.tb01924.x
Subject(s) - acanthosis nigricans , methyltestosterone , medicine , klinefelter syndrome , diabetes mellitus , dermatology , endocrinology , insulin resistance
Summary A patient with Klinefelter's syndrome, who developed acanthosis nigricans, diabetes mellitus and insulin resistance, is reported. The onset of these abnormalities occurred during therapy with methyltestosterone and we believe that this drug may have been responsible.