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Is remission of acne due to changes in sebum composition?
Author(s) -
MARSDEN J. R.,
MIDDLETON B.,
MILLS C.
Publication year - 1987
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1987.tb01846.x
Subject(s) - acne , composition (language) , medicine , dermatology , endocrinology , philosophy , linguistics
Summary Remission of acne is unlikely to be due to a reduction in sebum production as this remains increased despite the improvement. To investigate the possibility that remission may be due to changes in the composition of sebum, we have measured these changes in males of similar ages with severe acne, severe acne that was improving, and previous severe acne. There were no differences in the rates of synthesis of the five major sebaceous lipids between the three groups, and we conclude that remission of acne is unlikely to be due to changes in the composition of sebum.