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Cryosurgery of rhesus monkey skin—evaluation of epidermal thickening and effect on elastic component
Author(s) -
NATIELLA J.R.,
CARTER J.M.,
GAGE A.A.,
NATIELLA R.R.,
JOHNSON R.R.
Publication year - 1986
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1986.tb00496.x
Subject(s) - cryosurgery , liquid nitrogen , medicine , thickening , pathology , biomedical engineering , anatomy , surgery , chemistry , organic chemistry , polymer science
Summary The skin of the rhesus monkey was subjected to one and two‐cycle freezing with liquid nitrogen spray. Temperatures of –40 to –60°C were used and the sites were evaluated from 7 to 182 days. Overall healing was excellent. Long‐term specimens showed a consistent increase in epidermal thickness at the site of the freeze. This was quantified by use of computer‐assisted image analysis. In addition, the elastic component of the skin, seldom studied in repair following skin surgery, did not regenerate.