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Elastosis perforans serpiginosa and pseudoxanthoma elasticum‐like skin change due to D‐penicillamine
Author(s) -
MEYRICK THOMAS R.H.,
KIRBY J.D.T.
Publication year - 1985
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1985.tb00588.x
Subject(s) - pseudoxanthoma elasticum , cystinuria , penicillamine , medicine , dermatology , cutis , cutis laxa , cystine , biochemistry , chemistry , cysteine , enzyme
Summary High dose D‐penicillamine is used in the therapy of Wilson's disease and cystinuria. Elastosis perforans serpiginosa (Guilaine, Benhamou & Molas, 1972), penicillamine dermopathy (Sternleib & Scheinberg, 1964; Katz, 1967; Beer & Cooke, 1967), cutis hyperelastica (Charlebois, Cadotte & Barbeau, 1972), excessive skin wrinkling (Greer, Askew & Richardson, 1976) and pseudoxanthoma elasticum‐like skin change (Meyrick Thomas et al. , 1984) have all been documented as developing in consequence of such therapy. We report a patient in whom mild pseudoxanthoma elasticum‐like skin change and elastosis perforans serpiginosa developed, following high dose D‐penicillamine treatment for cystinuria.