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Immune findings in staphylococcal bullae—cross‐reactivity between epidermal and staphylococcal antigens
Author(s) -
GUILLET GERARD,
FIZET DOMINIQUE
Publication year - 1984
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1984.tb00847.x
Subject(s) - staphylococcal scalded skin syndrome , impetigo , antigen , immunology , immune system , pemphigus , direct fluorescent antibody , immunofluorescence , medicine , staphylococcus aureus , dermatology , biology , antibody , bacteria , genetics
Summary Pemphigus‐like patterns of direct immunofluorescence are reported in skin biopsies from children with bullous impetigo and the staphylococcal scalded‐skin syndrome (SSSS). Similar findings are observed with in vitro tests using normal human skin incubated with serum from a child with severe staphylococcal chest infection. These data suggest a possible immunological basis for the blistering phenomenon, with immunological cross reactions between epidermal and some types of staphylococcal antigens.