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Response of rosacea to isotretinoin
Author(s) -
MARSDEN J.R.,
SHUSTER SAM,
NEUGEBAUER M.
Publication year - 1984
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1984.tb00842.x
Subject(s) - isotretinoin , rosacea , medicine , erythema , dermatology , gastroenterology , acne
Summary We have treated seven patients with severe rosacea with 1 mg kg −1 day −1 isotretinoin for 12 weeks. There were large reductions in numbers of papules and pustules ( P < 0.001) small decreases in measurements of erythema ( P < 0.01) and median values for severity were lower during and after treatment. There was evidence of relapse by 8 weeks after stopping isotretinoin. Side‐effects were well tolerated and increases in serum lipids and indices of liver function had reversed by 4 weeks after treatment. We conclude that isotretinoin is effective in rosacea.