Premium
The prevalence of bone cysts in Darier's disease: a survey of 31 cases
Author(s) -
CRISP A.J.,
PAYNE C.M.E. ROWLAND,
ADAMS J.,
BRENTON D.P.,
THOMAS R.H. MEYRICK,
BLACK M.M.,
POPE F.M.,
WILKINSON J.D.,
MacDONALD LESLEY M.
Publication year - 1984
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1984.tb00759.x
Subject(s) - darier's disease , medicine , dermatology , disease , pathology
Summary There have previously been reports of an association between Darier's disease and bone cysts. A patient with Darier's disease is described in whom widespread cystic bone disease was attributable to severe dietary osteomalacia with secondary hyperparathyroidism. Vitamin D supplements have allowed considerable healing of the cysts although radiological defects persist. A limited skeletal survey of thirty other patients with Darier's disease failed to detect further examples of bone cysts and it is concluded that previous reports may represent only a chance association. The possibility that Darier's disease itself may predispose to osteomalacia and secondary hyperparathyroidism is discussed.