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Mycosis fungoides: a morphological study
Author(s) -
PUTTE S.C.J.,
MEER J.B.
Publication year - 1981
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1981.tb02269.x
Subject(s) - mycosis fungoides , pathology , biopsy , skin biopsy , dermatology , biology , medicine , lymphoma
Summary Skin biopsies from nineteen biopsy proven patients with mycosis fungoides were studied by using a contrasting dichrome stain in 0.5 μm thin sections, and comparing the results to those of normal skin and non‐lymphomatous dermatoses. An abnormal cellular component was observed in mycosis fungoides, consisting of cells that exhibited a great diversity in cellular morphology. In addition to large and small types of ‘mycosis cells’, variants with less indented nuclei and three types of blast cells were identified. Intermediate forms suggested a process of differentiation. All types showed a basic similarity in form to a normal lymphoid cell of human skin, but they differed by their larger size, more pronounced nuclear grooving and nuclear hyperchromasia.