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The Bazex Syndrome: follicular atrophoderma with multiple basal cell carcinomas, hypotrichosis and hypohidrosis
Author(s) -
PLOSILA M.,
KIISTALA R.,
NIEMI K.M.
Publication year - 1981
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1981.tb02265.x
Subject(s) - hypotrichosis , forehead , sweat , medicine , basal cell carcinoma , dermatology , sweat gland , apocrine , follicular phase , pathology , anatomy , basal cell , biology , biochemistry , gene
Summary The Bazex syndrome—follicular atrophoderma, basal cell carcinomas, hypotrichosis, hypohidrosis and some minor skin abnormalities—is described in a Finnish family. Local hypohidrosis was confirmed by measuring the water evaporation rate on the forehead skin. In histological samples from the forehead skin no sweat glands were found. The sweat response due to exercise or metacholine stimulation was slight or negligible. Histologically and ultrastructurally, follicular anomalies were a fundamental feature in the various skin lesions.