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Lack of effect of topically applied epidermal growth factor (EGF) on epidermal growth in man in vivo
Author(s) -
GREAVES M.W.
Publication year - 1980
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1980.tb01675.x
Subject(s) - epidermal growth factor , in vivo , medicine , growth factor , endocrinology , biology , receptor , microbiology and biotechnology
Summary Epidermal growth factor (EGF) has been applied daily to 6 mm diameter circular epidermal wounds in otherwise healthy adult volunteers, in dosage 5 /ug in O'T ml. Using complete closure of the wounds as an end‐point, no evidence of enhancement of epidermal growth at EGF‐treated sites was evident.