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Plane xanthoma developing in photosensitive eczema
Author(s) -
JAMES M.P.,
WARIN A.P.
Publication year - 1978
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1978.tb01503.x
Subject(s) - xanthoma , mechanism (biology) , medicine , dermatology , pathology , cholesterol , chemistry , physics , quantum mechanics
Summary Three cases of plane xanthoma arising in chronic eczema are described. Two patients had long standing photosensitive eczema and the other actinic reticuloid. It is suggested that foam cells develop from dermal macrophages in chronically inflamed skin. Lipid accumulation may be due to a failure of a specific receptor‐mediated control of cholesterol uptake into macrophages and be independent of circulating plasma lipid or lipoprotein levels.