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Eosinophil fluorescence in cutaneous infiltrates—a possible source of confusion
Author(s) -
HODGE L.,
BLACK M.M.,
GANGE R.W.
Publication year - 1978
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1978.tb01475.x
Subject(s) - fluorescein isothiocyanate , immunofluorescence , confusion , eosinophil , fluorescein , pathology , fluorescence , eosinophilic , cytoplasm , immunology , direct fluorescent antibody , antigen , medicine , chemistry , antibody , asthma , biochemistry , optics , psychology , psychoanalysis , physics
Summary Granular cytoplasmic cellular fluorescence was observed in a wide variety of dermatoses examined by immunofluorescence. This was shown to be due to non‐immunological binding of the fluorescein isothiocyanate label by eosinophils. Eosinophil fluorescence presents both a potential source of confusion in the interpretation of immunofluorescence procedures and a sensitive means for the recognition of eosinophils in cutaneous infiltrates.